Table 4.

Relation of the GDF-15 level and all-cause death in univariate and multivariate survival analysis

	Independent predictors of all-cause death
	Univariate Models			Multivariate Models
	HR	95% CI	P	HR	95% CI	P
Age	1.97	1.04–1.12	< 0.001	1.07	1.01–1.09	0.01
Sex	1.23	0.98–1.37	0.09	–	–	–
Smoking	0.87	0.80–1.17	0.39	–	–	–
BMI	0.99	0.95–1.02	0.48	–	–	–
Hypertension	0.98	0.74–1.28	0.87	–	–	–
Hyperlipidemia	1.54	1.38–1.76	0.02	1.48	1.38–1.86	0.03
DM	1.11	0.87–1.42	0.42	–	–	–
GDF-15 ≤ 1200 ng/L	1.11	0.87–1.42	0.42	–	–	–
GDF-15 ≤ 1800 ng/L	1.33	0.94–1.56	0.13	–	–	–
GDF-15 > 1800 ng/L	2.54	1.99–3.09	< 0.001	2.04	1.57–2.61	< 0.001