Table 1.
Results of in vivo faecal egg count reduction tests (FECRT) in goat herds A & B
| Groups | FECRT no. 1 – autumn 2017 | FECRT no. 2 – autumn 2018 | FECRT no. 3 – autumn 2019 | |||||
|---|---|---|---|---|---|---|---|---|
| Control | FBZ | IVM | LEV | Control | LEV | Control | LEV | |
| Herd A | ||||||||
| n | 8 | 8 | 8 | 8 | 10 | 10 | – | – |
| FEC [epg] pre-treatment | – | – | ||||||
| mean ± SD | 1769 ± 1396 | 1713 ± 1259 | 1731 ± 1278 | 1394 ± 1341 | 1175 ± 1212 | 1940 ± 1883 | ||
| median (IQR) | 1225 (750–2700) | 1225 (888–2363) | 1225 (950–2338) | 1025 (650–1488) | 650 (550–1500) | 1350 (513–2763) | ||
| range | 250–4250 | 400–3750 | 450–3700 | 250–4400 | 150–4300 | 250–6400 | ||
| FEC [epg] post-treatmenta | – | – | ||||||
| mean ± SD | 1606 ± 1384 | 1250 ± 810 | 1188 ± 1144 | 6 ± 18 | 815 ± 632 | 40 ± 97 | ||
| median (IQR) | 925 (763–2225) | 1225 (750–2700) | 750 (425–1463) | 0 (0–0) | 650 (375 − 1163) | 0 (0–0) | ||
| range | 350–4400 | 250–4250 | 200–3350 | 0–50 | 50–2100 | 0–300 | ||
| FECR%-1 [%] (CI 95%) | – | 22 (−70 to 64) (R)b | 26 (−89 to 71) (R) | 100 (97 to 100) (ND) | – | 95 (75 to 99) (S) | – | – |
| FECR%-2 [%] | – | 27 (R) | 31 (R) | 100 (ND) | – | 98 (ND) | – | – |
| FECR%-3 [%] | – | 20 (R) | 24 (R) | 100 (ND) | – | 97 (ND) | – | – |
| Herd B | ||||||||
| n | 6 | 5 | 5 | 5 | 10 | 10 | 22 | 21 |
| FEC [epg] pre-treatment | ||||||||
| mean ± SD | 3592 ± 2929 | 2750 ± 1065 | 3080 ± 1263 | 3230 ± 924 | 4390 ± 2314 | 6175 ± 3365 | 2355 ± 1779 | 2307 ± 1394 |
| median (IQR) | 2900 (1038–6000) | 3100 (2500–3250) | 3250 (2500–3700) | 3550 (2700–3800) | 3900 (2863–4763) | 4825 (4438–6750) | 2000 (875–3650) | 2100 (1250–3700) |
| range | 900 − 7400 | 1050–3850 | 1300–4650 | 1900–4200 | 2050–10,050 | 3500–14,750 | 200–5950 | 550–4900 |
| FEC [epg] post-treatmenta | ||||||||
| mean ± SD | 2658 ± 1404 | 2950 ± 937 | 250 ± 252 | 70 ± 157 | 4980 ± 2376 | 665 ± 652 | 1911 ± 1437 | 1471 ± 1315 |
| median (IQR) | 2250 (1863–2825) | 3000 (2250–3200) | 100 (50–500) | 0 (0–0) | 4275 (4075–5038) | 400 (225–913) | 1500 (800–2788) | 1350 (600–1950) |
| range | 1400–5300 | 1950–4350 | 50–550 | 0–350 | 2250–11,000 | 0–2000 | 200–5300 | 0–5300 |
| FECR%-1 [%] (CI 95%) | – | –11 (−88 to 35) (R) | 91 (74 to 97) (R) | 97 (79 to 100) (ND) | – | 87 (73 to 93) (R) | – | 23 (−29 to 54) (R) |
| FECR%-2 [%] | – | –7 (R) | 92 (R) | 98 (ND) | – | 89 (R) | – | 36 (R) |
| FECR%-3 [%] | – | −45 (R) | 89 (ND) | 97 (ND) | – | 91 (ND) | – | 21 (R) |
n number of animals in the group
FBZ fenbendazole, IVM ivermectin, LEV levamisole
FEC faecal egg count, epg eggs per gram, FECR% faecal egg count reduction percentage
a 14 days post-treatment in the autumn 2017, 5–7 days post-treatment in the autumn 2018 and 2019
b anthelmintic resistance: R – confirmed, S – suspected, ND – not detected