Figure 2 |. Mono-ubiquitinated human ID^Ub complex bound to nicked DNA.

a, Overall ID^Ub-DNA structure with FANCD2^Ub pink (labeled D2), FANCI^Ub cyan (I), FANCI ubiquitin (Ub^I) green, FANCD2 ubiquitin (Ub^D2) red, and DNA yellow. The N and C termini are labeled (FANCD2 N-terminus obscured in this view). FANCI is oriented as in Fig. 1b. b, View looking down the left side of the horizontal axis of a. c, Cryo-EM density without temperature-factor sharpening. Orientation as in b, but parts of FANCD2 are cropped to reveal the internal DNA (red, density yellow).