Table 6.
Estimated bioavalibity of trans-resveratrol (RES), trans-resveratrol-3-sulfate (R3S) and resveratrol-3-O-β-D-glucuronide (R3G) in male and female HSD rats and B6C3F1/N mice following gavage administration of RES
| RES (%) | R3S (%) | R3G (%) | ||||
|---|---|---|---|---|---|---|
| Male | Female | Male | Female | Male | Female | |
| Rats | ||||||
| 312.5 mg/kg | 15.1 | 21.0 | 38.2 | 57.5 | 68.7 | 65.0 |
| 625 mg/kg | 11.5 | 15.1 | 36.1 | 67.6 | 38.6 | 35.0 |
| 1250 mg/kg | 23.7 | 30.6 | 68.5 | 63.1 | 102.0 | 43.8 |
| Mice | ||||||
| 625 mg/kg | 3.3 | 4.2 | 42.2 | 13.0 | 63.6 | 66.0 |
| 1250 mg/kg | 2.6 | 5.9 | 15.8 | 9.4 | 37.3 | 55.8 |
| 2500 mg/kg | 3.0 | 2.5 | 10.4 | 4.5 | 30.5 | 57.8 |