Figure 2. Platinum compound treatment causes increased ROS levels at 24 but not 48 hours post treatment in HEI-OC1 cells.
A. At 24 hours, cisplatin, phenanthriplatin and pyriplatin treatment caused elevated ROS production compared to the control. B. At 48 hours, ROS levels are not significantly different than control for all three platinum compounds. Labeling: Positive control (+), negative control (−), cisplatin (Cis), phenanthriplatin (Phen), pyriplatin (Pyri). Error bars represent standard error of the mean. N = 3; “****”, p < 0.0001 (p value comparison to negative control).