Figure 3. Platinum compound treatment does not induce mitochondrial membrane depolarization at either 24 or 48 hours post treatment in HEI-OC1 cells.
A. At 24 hours, only the positive control caused mitochondrial membrane depolarization. B. At 48 hours, only the positive control caused mitochondrial membrane depolarization. Labeling: Positive control (+), negative control (−), cisplatin (Cis), phenanthriplatin (Phen), pyriplatin (Pyri). Error bars represent standard error of the mean. N = 3; “***”, p < 0.001; “****”, p < 0.0001 (p value comparison to negative control).