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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Neurotoxicology. 2020 May 13;79:104–109. doi: 10.1016/j.neuro.2020.04.005

Figure 4. Platinum compound treatment decreased caspase-3/7 activity at 24 hours, and cisplatin increased caspase-3/7 activity at 48 hours in HEI-OC1 cells.

Figure 4.

A. At 24 hours, platinum compounds caused decreased caspase-3/7 activity, while the positive control increased caspase-3/7 activity. B. At 48 hours, cisplatin and the positive control caused increased caspase-3/7 activity, while phenanthriplatin and pyriplatin are not different than the negative control treatment. Labeling: Positive control (+), negative control (−), cisplatin (Cis), phenanthriplatin (Phen), pyriplatin (Pyri). Error bars represent standard error of the mean. N = 3; “**”, p < 0.01; “***”, p < 0.001; “****”, p < 0.0001 (p value comparison to negative control).