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. 2020 Jul 22;9:e55415. doi: 10.7554/eLife.55415

Figure 5. SIRT2 targets histone and non-histone proteins in Mtb-specific T-cells to ameliorate anti-mycobacterial host immune responses.

Figure 5.

(A) Schematic representation of the experimental plan. (B) Gating strategy utilized to analyze the intracellular levels of (C) SIRT2, (D) H3K18ac and (E) acetylated NFκB p65. Data shown is representative of at least two independent experiments each performed in triplicates. Data is represented as mean ± SD (n = 3). *p<0.05, **p<0.005, ***p<0.0005.

Figure 5—source data 1. SIRT2 deacetylates H3K18 and NFκB-p65 in Mtb-specific T cells.
Source data for Figure 5C, D and E.