Skip to main content
. Author manuscript; available in PMC: 2021 Jun 18.
Published in final edited form as: Chem Commun (Camb). 2020 May 12;56(48):6551–6554. doi: 10.1039/d0cc02107e

Figure 1.

Figure 1.

Immunization with the anti-Gal-assisted vaccines induced the production of anti-fentanyl antibodies. (A) Vaccination schedule used in this study. Anti-Gal antibody induction was carried out before week 0. Antinoc. stands for antinociception assay. Drug Distrib. stands for drug distribution study. (B) Midpoint anti-fentanyl IgG titers of sera from the vaccinated groups (n = 7 or 8) shown as means ± SEM. Fentanyl-bovine serum albumin conjugate (Fent-BSA) was used as the coating antigen in ELISA. **P < 0.01, ***P < 0.001 versus control, Brown-Forsythe and Welch ANOVA test.