TABLE 7.
Study 2 heterogeneity of diet effects in PAI-1: participants with or without MetSyn1
| All (n = 85) | With MetSyn (n = 20) | Without MetSyn (n = 65) | Difference: with vs. without | Difference: P value | |
|---|---|---|---|---|---|
| AAD | 4.54 ± 0.372 | 5.04 ± 0.482 | 4.03 ± 0.392 | 1.02 ± 0.473 | 0.03174 |
| MUFA | 4.65 ± 0.37 | 4.90 ± 0.48 | 4.41 ± 0.39 | 0.49 ± 0.47 | 0.2956 |
| Step 1 | 4.77 ± 0.37 | 5.56 ± 0.48 | 3.99 ± 0.39 | 1.57 ± 0.47 | 0.0009 |
| MUFA − AAD | 0.12 ± 0.153 | −0.15 ± 0.25 | 0.38 ± 0.14 | −0.52 ± 0.295 | 0.0732 |
| Step 1 − AAD | 0.24 ± 0.15 | 0.52 ± 0.26 | −0.04 ± 0.14 | 0.56 ± 0.29 | 0.0570 |
| Step 1 − MUFA | 0.12 ± 0.15 | 0.66 ± 0.26 | −0.42 ± 0.14 | 1.08 ± 0.29 | 0.0003 |
1
All analytes were measured in plasma. AAD, average American diet; MetSyn, metabolic syndrome; PAI-1, plasminogen activator inhibitor 1.
2
Entry is the estimated mean ± 1 SE obtained via a linear mixed-effects model accounting for diet, feeding period, center, race, gender/age group, MetSyn, and terms representing diet-by-MetSyn interactions.
3
Entry is the estimated mean difference ± 1 SE obtained from the same model.
4
The P value for the test of the null hypothesis that the difference is zero in the target population from which the sample was drawn.
5
Entry is the estimated difference of mean differences ± 1 SE obtained from the same model.