TABLE 1.

Maternal arterial biochemistry in CON and LEU sheep¹

	CON	LEU	P value
Whole blood hemoglobin, g/dL	5.95 ± 0.20	5.79 ± 0.13	0.51
Whole blood pH	7.46 ± 0.01	7.45 ± 0.01	0.70
Whole blood pCO2, mm Hg	34.7 ± 0.9	35.8 ± 0.9	0.40
Whole blood pO2, mm Hg	89.8 ± 2.2	91.4 ± 2.3	0.61
Whole blood hemoglobin-O2 saturation, %	97.4 ± 0.9	95.6 ± 0.9	0.18
Whole blood O2 content, mmol/L	5.6 ± 0.2	5.4 ± 0.1	0.34
Plasma glucose, mmol/L	3.5 ± 0.1	3.4 ± 0.1	0.14
Plasma lactate, mmol/L	0.7 ± 0.0	0.7 ± 0.1	0.88
Plasma amino acids, μmol/L
Alanine	145 ± 10	135 ± 11	0.50
Arginine	180 ± 11	169 ± 16	0.58
Asparagine	51 ± 5	48 ± 6	0.71
Aspartate	7 ± 1	7 ± 1	0.88
Cystine	23 ± 2	23 ± 2	0.88
Glutamate	56 ± 4	51 ± 4	0.42
Glutamine	337 ± 38	254 ± 17	0.06
Glycine	420 ± 43	461 ± 40	0.49
Histidine	55 ± 2	51 ± 3	0.32
Isoleucine	114 ± 9	101 ± 6	0.23
Leucine	142 ± 15	135 ± 7	0.69
Lysine	154 ± 16	157 ± 14	0.89
Methionine	33 ± 3	34 ± 2	0.84
Phenylalanine	63 ± 4	59 ± 4	0.44
Proline	119 ± 8	94 ± 9	0.07
Serine	82 ± 9	84 ± 9	0.88
Taurine	51 ± 6	50 ± 8	0.98
Threonine	172 ± 16	156 ± 20	0.53
Tryptophan	39 ± 3	39 ± 2	0.88
Tyrosine	77 ± 5	70 ± 5	0.30
Valine	225 ± 25	226 ± 12	0.98

¹Values are means ± SEs for CON (n = 8) and LEU (n = 9) groups. Measurements were made immediately before the fetal insulin secretion study. CON, control; LEU, leucine-infused; pCO₂, partial pressure of carbon dioxide; pO₂, partial pressure of oxygen.