TABLE 3.
Serum lipid concentrations by BCO1-rs6564851 genotype variants calculated using general linear models and adjusted for age, sex, BMI, retinol intake, and β-carotene intake1
| P value | ||||||
|---|---|---|---|---|---|---|
| Genotype | Additive model: | Dominant model: | Recessive model: | |||
| Variables | GG | GT | TT | GG vs GT vs TT | GG vs GT/TT | TT vs GG/GT |
| n | 130 | 227 | 118 | 130 vs 345 | 118 vs 357 | |
| Serum TC, mg/dL | 175 ± 3 | 165 ± 2 | 166 ± 3 | 0.04 | 0.011 | 0.47 |
| Serum non–HDL-C, mg/dL | 124 ± 3 | 114 ± 2 | 115 ± 3 | 0.009 | 0.002 | 0.46 |
| Serum HDL-C, mg/dL | 48.3 ± 1.0 | 49.7 ± 0.8 | 49.5 ± 1.1 | 0.96 | 0.79 | 0.96 |
| Serum TGs, mg/dL | 102 ± 4 | 96.4 ± 2.4 | 99.2 ± 3.5 | 0.39 | 0.23 | 0.82 |
1
Values are means ± SEMs. Statistical significance was set to P < 0.05. After applying the Bonferroni correction to consider the measurement of 3 independent tests (TC, HDL-C, and TG), we established the Bonferroni critical value to P < 0.017. BCO1, β-carotene oxygenase 1; HDL-C, HDL cholesterol; non–HDL-C, non–HDL cholesterol; TC, total cholesterol; TG, total triglyceride.