TABLE 2.

Age-adjusted Spearman correlation coefficients for vitamin D biomarkers and cardiometabolic biomarkers among postmenopausal women, stratified by race¹

Biomarkers	Total 25(OH)D	Fasting glucose	Fasting insulin	PTH	eGFR	hs-CRP	HOMA-IR	HOMA-B
All participants (n = 2800)
Total 25(OH)D	1	−0.13**	−0.26**	−0.37**	−0.16**	−0.14**	−0.26**	−0.17**
Fasting glucose		1	0.49**	0.07**	0.06**	0.18**	0.62**	−0.14**
Fasting insulin			1	0.17**	0.03	0.36**	0.98**	0.73**
PTH				1	0.01	0.08**	0.16**	0.14**
eGFR					1	0.04	0.04*	−0.04*
hs-CRP						1	0.36**	0.25**
HOMA-IR							1	0.61**
HOMA-B								1
American white women (n = 1500)
Total 25(OH)D	1	−0.12**	−0.24**	−0.29**	−0.05*	−0.08**	−0.23**	−0.19**
Fasting glucose		1	0.47**	0.06*	0.04	0.1**	0.58**	−0.08**
Fasting insulin			1	0.11**	−0.01	0.31**	0.99**	0.81**
PTH				1	0.003	0.05	0.11**	0.08**
eGFR					1	0.02	−0.002	−0.04
hs-CRP						1	0.3**	0.28**
HOMA-IR							1	0.71**
HOMA-B								1
American black women (n = 1300)
Total 25(OH)D	1	−0.07**	−0.12**	−0.36**	−0.06*	−0.05	−0.13**	−0.05
Fasting glucose		1	0.5**	0.05	0.06*	0.24**	0.67**	−0.24**
Fasting insulin			1	0.16	−0.03	0.35**	0.97**	0.64**
PTH				1	−0.07*	0.04	0.13**	0.15**
eGFR					1	−0.01	0.004	−0.11**
hs-CRP						1	0.37**	0.18**
HOMA-IR							1	0.46**
HOMA-B								1

¹Age-adjusted Spearman partial correlation coefficients were calculated to examine the correlations of vitamin D biomarkers with each of the following cardiometabolic biomarkers. Among all participants, the SDs of vitamin D biomarkers and cardiometabolic biomarkers were 20.90 for 25(OH)D, 28.33 for fasting glucose, 8.11 for fasting insulin, 20.66 for PTH, 15.98 for eGFR, 6.76 for hs-CRP, 3.70 for HOMA-IR, and 62.19 for HOMA-B. *P < 0.05; **P < 0.01. eGFR, estimated glomerular filtration rate; HOMA-B, homeostasis model assessment of β-cell function; hs-CRP, high-sensitivity C-reactive protein; PTH, parathyroid hormone; 25(OH)D, 25-hydroxyvitamin D.