Table 4.
Regression model of total morphine use for patients undergoing unilateral bipedicled (n=17) and unilateral unipedicled (n=65) DIEP reconstructions at different timepoints
| Parameter | Total morphine use after 12 hr (mg) |
Total morphine use after 24 hr (mg) |
Total morphine use after 48 hr (mg) |
||||
|---|---|---|---|---|---|---|---|
| Co-efficient | P-value | Co-efficient | P-value | Co-efficient | P-value | ||
| Age at operation (yr) | –0.18 | 0.34 | 0.51 | 0.086 | –1.16 | 0.013 | |
| Body mass index (kg/m2) | 0.02 | 0.95 | 0.12 | 0.84 | –0.27 | 0.76 | |
| Timing of reconstruction | Delayeda) | –4.03 | 0.33 | –10.10 | 0.12 | –12.40 | 0.23 |
| Immediate | Reference | Reference | Reference | ||||
| Smoking status | Non-smokera) | –12.10 | 0.049 | –25.70 | 0.010 | –38.47 | 0.01 |
| Smoker | Reference | Reference | Reference | ||||
| Diabetic comorbidity | Non-diabetica) | 13.90 | 0.16 | 16.10 | 0.31 | 14.60 | 0.55 |
| Diabetic | Reference | Reference | Reference | ||||
| Chemotherapy | No chemotherapya) | 4.61 | 0.34 | 13.90 | 0.07 | 25.50 | 0.03 |
| Experienced chemotherapy | Reference | Reference | Reference | ||||
| Radiotherapy | No radiotherapya) | –5.13 | 0.21 | –7.20 | 0.26 | –5.39 | 0.59 |
| Experienced radiotherapy | Reference | Reference | Reference | ||||
| Type of reconstruction | Bipedicleda) | –8.73 | 0.038 | –10.50 | 0.11 | –13.90 | 0.18 |
| Unipedicled | Reference | Reference | Reference | ||||
DIEP, deep inferior epigastric artery perforator.
a)
The co-efficient describing the effect of the binary parameters on the total morphine use. For example, for smoking status the co-efficient and P-values are listed in terms of the effect of being a “non-smoker.” Statistically significant, P<0.05.