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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: J Allergy Clin Immunol. 2020 Feb 4;146(2):390–405. doi: 10.1016/j.jaci.2020.01.038

Figure 4.

Figure 4.

Comparison of blood and bronchoalveolar lavage (BAL) ILC2 populations in asthmatic patients and disease controls (DC). A: PBMCs from 18 asthmatic patients and 12 disease controls were cultured in the medium alone for 5 days and then analyzed for IL5+ ILC2 populations. The frequency of IL5+lin- cells is presented as % PBMCs. ILC B: BAL cells from 34 asthmatic patients and 16 disease controls were stained ex vivo for IL5+ (CD45+Lin-) ILC2 populations by flow cytometry. The frequency of IL5+ ILCs is presented as % BAL cells. Statistical significance (Mann-Whitney U test) is shown at the top of the dot plots. C& D: Correlation (r) between BAL eosinophils and BAL IL5+ CRTH2+ ILC2s (C) and BAL total IL5+ ILC2s (CRTH2+, IL7Rα+ and DN).