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. 2020 Jul 22;15:5181–5202. doi: 10.2147/IJN.S247692

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© 2020 AbouAitah et al.

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XRD and DSC measurements.

Notes: XRD patterns of all prepared materials. Starting from the bottom: nanoparticles, modified nanoparticles, nanoformulations, combined nanoformulations, and pure prodrugs (A).DSC spectra obtained for materials. Starting from the bottom: nanoparticles, modified nanoparticles, nanoformulations, combined nanoformulations, and pure prodrugs (B).

Abbreviations: XRD, X-ray powder diffraction; DSC, differential scanning calorimetry analysis; P.M. 2–3D – SH-QR is a physical mixture of prodrugs and MSNs; MSNs, mesoporous silica nanoparticles; MSNs-NH₂, MSNs modified amino groups; MSNs-NH₂-SH, MSNs-NH₂ loaded SH; MSNs-NH₂-QR, MSNs-NH₂ loaded QR; MSNs-NH₂-SH-QR, MSNs-NH₂ loaded SH and QR; SH, shikimic acid; QR, quercetin.