Table 1.
Properties of Astrolabe, Aldy, and Stargazer.
| Tool | OS | Language | Central feature | NGS data | Input/ref | Output |
|---|---|---|---|---|---|---|
| Astrolabe | Linux | Java | Probabilistic | WGS | VCF | Diplotypes |
| Mac | scoring system | PGRNseqa | BAM | Suballeles | ||
| b37, b38 | Phenotype | |||||
| All novel SNVs | ||||||
| Aldy | Linux | Python | Combinatorial | WGS | BAM | Diplotypes |
| Mac | framework | PGRNseq | b37 | Suballeles | ||
| Putative novel | ||||||
| core variants | ||||||
| Stargazer | Linux | Python | Statistical | WGS | VCF | Diplotypes |
| Mac | phasing | PGRNseq | GDF | Phenotype | ||
| b37 | All novel SNVs |
aNot yet optimised for Astrolabe’s CNV calling.