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. 2020 Aug 3;10:13031. doi: 10.1038/s41598-020-69007-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Antibody responses can persist at high levels for up to a decade. (A) Estimated asymptote and time-average mean antibody response are shown for IgG responses to gp140. Only regimens with participants who still had levels of that antibody $> 100$ Net MFI after 180 days are included. (B) IgG response levels against gp140 shown for all individuals in HVTN 205 with day 0 representing peak response at 2 weeks after vaccination.