Table 1.
Trial arm | Strategy | Products | Envelope | Month | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
0 | 1 | 2 | 3 | 4 | 6 | 8 | 10 | ||||
097-T1 | CCPP | vCP1521, AIDSVAX | gp120 | C | C | C + P | C + P | ||||
097-T2 | CCPP | vCP1521, AIDSVAX | gp120 | C | C | C + P | C + P | ||||
105-T2 | DDPP | HIV-PT123, AIDSVAX | gp140, gp120 | D | D | P | P | ||||
105-T3 | DDD/P | HIV-PT123, AIDSVAX | gp140, gp120 | D | D | D + P | D + P | ||||
105-T4 | D+P | HIV-PT123, AIDSVAX | gp140, gp120 | D + P | D + P | D + P | D + P | ||||
094-T1 | DDMM | GEO-D03, MVA/HIV62B | gp160, gp150 | D | D | M | M | M | |||
094-T2 | DDMMM | GEO-D03, MVA/HIV62B | gp160, gp150 | D | D | M | M | M | |||
094-T3 | DDMM | GEO-D03, MVA/HIV62B | gp160, gp150 | D | D | M | M | ||||
205-T1+3 | DDMM | JS7, MVA/HIV62 | gp160, gp150 | D | D | M | M | ||||
205-T4 | MMM | MVA/HIV62 | gp160, gp150 | M | M | M |
Main trials considered in this study (additional trials are in Supplementary information). Envelope gives which component of the envelope was included in the trial vaccines. Blank indicates no injection given at month. All protein vaccines here use AIDSVAX B/E. C indicates Canarypox vector, P indicates protein, D indicates DNA, rAd represents recombinant adenovirus and M represents Modified vaccinia ankara.