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. 2020 Aug 3;10:266. doi: 10.1038/s41398-020-00956-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Locomotor activity expressed as the mean (±SEM) is shown for total distance traveled in meters (m) across a 1-h session. Rats were pretreated 30min prior to the start of the session with either vehicle, SB224289 (10 mg/kg, s.c.) or BRL15572 (0–3.0 mg/kg, i.p.). Rats in the SB224289 experiment received a second pretreatment of either vehicle or zolmitriptan (5.6 mg/kg, s.c.) 15min later. There were no main effects nor interactions; data are collapsed across male (n = 6) and female (n = 7) rats.