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. 2020 Aug 3;10:12996. doi: 10.1038/s41598-020-69787-1

Table 1.

Summary of the marker genes and immune cells in the TME.

Cell type Selected marker genes
B cells BLK, CD19, FCRL2, MS4A1, KIAA0125, TNFRSF17, TCL1A, SPIB, PNOC
CD45+ cells PTRPC
Cytotoxic cells PRF1, GZMA, GZMB, NKG7, GZMH, KLRK1
Dendritic cells KLRB1, KLRD1, CTSW, GNLY, CCL13, CD209, HSD11B1
Exhausted CD8+ cells LAG3, CD244, EOMES, PTGER4
Macrophages CD68, CD84, CD163, MS4A4A
Mast cells TPSB2, TPCAB1, CPA3, MS4A2, HDC
Neutrophils FPR1, SIGLEC5, CSF3R, FCAR, FCGR3B, CEACAM3, S100A12
NK CD56dim cells KIR2DL3, KIR2DL1, KIR2DL2, IL21R
NK cells XCL1, XCL2, NCR1
T cells CD6, CD3D, CD3E, SH3E, SH2D1A, TRAT1, CD3G
Th1 cells TBX21
Tregs FOXP3
CD8+ T cells CD8A, CD8B

NK natural killer; Th1 type 1T helper; Tregs regulatory T cells.