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. 2020 Aug 3;11:3869. doi: 10.1038/s41467-020-17681-9

Fig. 8. Proposed catalytic cycle.

Fig. 8

The in situ formed chiral catalyst [Y*] catalyzes isomerization of E-1a into E/Z-10 in the presence of NEt3, followed by nucleophilic addition of E-1a and protonation to deliver the final product 2a.