Table 2.
Effect of AMDE on haematological indices of the treated wistar rats.
| Control | AMDE1 | AMDE2 | AMDE3 | |
|---|---|---|---|---|
| WBC (x109/L) | 9.0 ± 0.2 | 10.4 ± 0.5 | 10.8 ± 0.7 | 10.3 ± 0.6 |
| LYMPH (%) | 77.3 ± 2.8 | 83.0 ± 4.6 | 72.0 ± 4.5 | 83.3 ± 5.0 |
| MID (%) | 10.0 ± 0.9 | 7.7 ± 0.3 | 7.0 ± 0.3 | 9.3 ± 0.2 |
| GRAN (%) | 9.5 ± 0.5 | 9.3 ± 0.6 | 7.7 ± 0.8 | 8.3 ± 0.2 |
| HGB (g/dL) | 17.9 ± 1.0 | 16.0 ± 2.3 | 15.1 ± 0.6 | 14.1 ± 0.6a |
| RBC (x1012/L) | 9.0 ± 0.4 | 8.3 ± 0.4 | 7.8 ± 0.1 | 7.2 ± 0.3a |
| HCT (%) | 53.3 ± 3.4 | 49.4 ± 6.9 | 47.1 ± 1.9 | 42.1 ± 1.5a |
| MCV (fL) | 58.6 ± 3.5 | 59.9 ± 3.3 | 55.4 ± 2.6 | 56.7 ± 0.5 |
| MCH (pg) | 19.8 ± 1.4 | 19.3 ± 0.8 | 20.3 ± 1.0 | 19.1 ± 0.5 |
| MCHC (g/dL) | 33.4 ± 1.5 | 32.4 ± 0.7 | 32.1 ± 0.3 | 33.4 ± 1.0 |
| RDW-SD (fL) | 36.6 ± 2.9 | 33.3 ± 1.0 | 35.3 ± 3.0 | 33.4 ± 1.0 |
| PLT (x109/L) | 426.7 ± 74.6 | 452.00 ± 60.2 | 495.3 ± 79.4 | 415.7 ± 52.6 |
| MPV (fL) | 8.7 ± 0.1 | 8.60 ± 0.2 | 8.7 ± 0.3 | 8.9 ± 0.2 |
| PDW | 14.6 ± 0.5 | 14.43 ± 0.5 | 14.9 ± 0.1 | 15.1 ± 0.1 |
| PCT (%) | 0.4 ± 0.0 | 0.39 ± 0.1 | 0.4 ± 0.1 | 0.4 ± 0.1 |
AMDE1: Group administered with AMDE (200 mg/kgbw), AMDE2: Group administered with AMDE (400 mg/kgbw), AMDE3: Group administered with AMDE (600 mg/kgbw). Values are mean ± SEM, n = 6. Superscripts: Values bearing superscript (a) across a row are statistically different from that of control (p > 0.05). WBC: White Blood Cell Count, LYMPH: Lymphocytes, MID: MID cells, GRAN: Granulocyte, HGB: Total haemoglobin, RBC: Red blood cell count, HCT: Haematocrit, MCV: Mean Corpuscular Volume, MCH: Mean Corpuscular Haemoglobin, MCHC: Mean Corpuscular Haemoglobin Concentration, RDW-CV: Red Cell Distribution Width, PLT: Platelet count, MPV: Mean Platelet Volume, PDW: Platelet Distribution Width, PCT: Plateletcrit.