Table 3.
Effect of AMDE on the liver and kidney function indices of the treated wistar rats.
| Control | AMDE1 | AMDE2 | AMDE3 | |
|---|---|---|---|---|
| *AST(U/L) | 83.20 ± 2.94a | 88.70 ± 1.27 a | 82.60 ± 6.90 a | 80.40 ± 7.90 a |
| *ALT(U/L) | 58.80 ± 2.30 b | 61.40 ± 2.60 b | 59.00 ± 3.20b | 59.40 ± 1.80 b |
| *ALP(U/L) | 65.60 ± 12.70 c | 56.40 ± 3.10 c | 59.10 ± 7.00c | 65.70 ± 10.00 c |
| *TOTAL BILIRUBIN (mg/dl) |
0.74 ± 0.07d | 0.72 ± 0.05d | 0.68 ± 0.07d | 0.67 ± 0.04d |
| *DIRECT BILIRUBIN (mg/dl) |
0.33 ± 0.03e | 0.32 ± 0.02e | 0.30 ± 0.03e | 0.29 ± 0.02e |
| *ALBUMIN (g/dl) |
6.07 ± 0.24f | 6.05 ± 0.24f | 6.08 ± 0.28f | 6.05 ± 0.45f |
|
#CREATININE (mg/dl) |
1.04 ± 0.03g | 1.10 ± 0.03g | 1.08 ± 0.08g | 0.94 ± 0.04g |
| #UREA(mg/dl) | 59.9 ± 1.06h | 61.02 ± 7.10h | 56.90 ± 5.60h | 53.50 ± 6.80h |
|
#SODIUM (mEq/L) |
296.58 ± 87.90i | 297.42 ± 65.25i | 294.50 ± 41.61i | 294.33 ± 23.23i |
|
#CHLORIDE (mEq/L) |
109.63 ± 10.08 j | 102.22 ± 8.25 j | 126.54 ± 21.49 j | 116.07 ± 24.38j |
|
#POTASSIUM (mEq/L) |
7.176 ± 0.10 k | 6.838 ± 0.21 k | 8.081 ± 0.23 k | 5.975 ± 0.22 k |
AMDE1: Group administered with AMDE (200 mg/kgbw), AMDE2: Group administered with AMDE (400 mg/kgbw), AMDE3: Group administered with AMDE (600 mg/kgbw). Values are mean ± SEM, n = 6. Superscripts: Values bearing the same superscript across a row are not statistically different (p>0.05).* Liver function indices, # Kidney function indices.