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. 2020 Jul 28;14:750. doi: 10.3389/fnins.2020.00750

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Copyright © 2020 Jia, Chen, Geng, Cheng, Li, Qiu, Huang, Wang, Zhang and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Glutamate chemical exchange saturation transfer imaging in vivo in encephalitis rats. (A) T2_W imaging and GluCEST map of encephalitis rats with Staphylococcus aureus infections at different time points (0, 3, and 7 days), suggesting that the GluCEST signal was increased with increasing time; statistically significant differences were found among the different time points [0 days vs 3 days (B), 0 days vs 7 days (C), and 3 days vs 7 days (D), n = 27, Student’s t test, two-tailed, unpaired, ****p < 0.0001].