Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 28;14:750. doi: 10.3389/fnins.2020.00750

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Jia, Chen, Geng, Cheng, Li, Qiu, Huang, Wang, Zhang and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Glutamate chemical exchange saturation transfer imaging in vivo of patients with encephalitis and lacunar infarction. (A) Conventional T2w imaging, T2Flair, and diffusion-weighted images (DWI) could not discriminate encephalitis and lacunar infarction (LI), but GluCEST MRI could distinguish between them. (B) Z-spectrum demonstrated that a small signal dip at 3.0 ppm (green circle) was observed in the inflamed regions but not observed in the LI regions, indicating that inflammation is a cause of the elevated local glutamate concentration. (C) GluCEST signal was elevated in patients with encephalitis and decreased in patients with LI (n = 6, Student’s t test, two-tailed, unpaired, ****p < 0.0001).