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. 2020 Jul 28;11:1632. doi: 10.3389/fimmu.2020.01632

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Copyright © 2020 Chodisetti, Fike, Domeier, Choi, Soni and Rahman.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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B10 cells show higher STAT1 and IFNγR expression. Representative flow cytometric gating strategy (A,B,E,F) and overlay histograms (C,G) show expression of IFNγR (C), and total STAT1 (G) in indicated cell populations derived from Sle1b mice. The bar diagrams show geometric mean fluorescence of IFNγR (D) and STAT1 (H) in CD19⁺ total B cells, CD1d^hiCD5⁺ B10 cells, CD1d^loCD5⁻ non-B10 cells from B6 and Sle1b mice. These data represent 2 independent experiments. Statistical analysis was performed by one-way ANOVA, with a follow-up Tukey multiple-comparison test. ns, non-significant, **p < 0.01, and ****p < 0.0001.