TABLE 1.

AP parameters of atrial- and ventricular-like hiPSC-CMs in absence and presence of 4-AP.

	Atrial-like hiPSC-CMs (n = 11)		Ventricular-like hiPSC-CMs (n = 10)
	Baseline	4-AP	Baseline	4-AP
RMP (mV)	−81.31 ± 0.43	−80.83 ± 0.65	−75.52 ± 1.69*	−74.92 ± 1.71#
dV/dtmax (V/s)	74.54 ± 13.10	76.47 ± 13.41	83.70 ± 20.21	94.33 ± 24.43
APA (mV)	96.61 ± 2.66	98.33 ± 1.44	105.61 ± 3.69	104.59 ± 3.88
APD20 (ms)	35.86 ± 4.35	38.13 ± 4.69	77.73 ± 11.59*	68.68 ± 10.67‡#
APD50 (ms)	60.99 ± 5.55	65.05 ± 5.38	127.93 ± 19.67*	119.41 ± 18.09‡#
APD90 (ms)	81.27 ± 6.37	86.76 ± 5.92†	155.01 ± 21.49*	147.68 ± 20.38‡#
APPlatA (mV)	53.61 ± 5.25	60.53 ± 4.53†	89.61 ± 4.51*	89.42 ± 4.30#

Data are AP parameters (mean ± SEM) of APs elicited at 1 Hz in absence (baseline) and presence of 50 μM 4-aminopyridine (4-AP). *P < 0.05 atrial- vs. ventricular-like hiPSC-CMs (baseline); ^†P < 0.05 4-AP vs. baseline of atrial-like hiPSC-CMs; ^‡P < 0.05 4-AP vs. baseline of ventricular-like hiPSC-CMs; ^#P < 0.05 atrial- vs. ventricular-like hiPSC-CMs (4-AP).