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. 2020 Jul 28;8:405. doi: 10.3389/fped.2020.00405

Table 2.

Summary risk estimates of the association of LBW and premature with the risk of metabolic syndrome.

Subgroup No. of studies Pooled OR (95% CI) I2 (%) Pheterogeneity P-value between subgroups
LBW All studies 11 1.37 (1.17–1.61) 43.6 0.060
Study design
Cohort study 6 1.79 (1.39–2.31) 0.0 0.712 0.007
Cross-sectional study 5 1.22 (1.04–1.43) 46.1 0.115
Continent
Asia 3 1.66 (1.21–2.29) 0.0 0.817 0.023
Europe 5 1.69 (1.23–2.33) 23.7 0.263
South America 3 1.18 (1.00–1.39) 55.9 0.104
Gender
Both 7 1.37 (1.04–1.79) 35.0 0.161 0.464
Male 2 1.59 (0.58–4.38) 79.7 0.026
Female 2 1.39 (1.06–1.83) 50.7 0.154
Premature All studies 5 1.48 (1.00–2.21) 62.5 0.030
After excluding one study (RR >3.0) 4 1.30 (1.04–1.62) 9.5 0.345
Study design
Cohort studies 4 1.72 (1.12–2.65) 54.5 0.086 0.043
Cross-sectional studies 1 0.86 (0.52–1.42) NA NA

CI, confidence interval; LBW, low birth weight; NA, not available; RR, relative risk.