Table 1.
Variable | Control | PD | P value |
---|---|---|---|
Age (years) | 71.61 ± 4.99 | 71.48 ± 4.66 | 0.90 |
N (Male/Female) | 45 (25/20) | 50 (29/21) | 0.89 |
Education (years) | 15 ± 3.15 | 13.9 ± 2.97 | 0.09 |
Hypertension | 32/13 | 36/14 | 0.85 |
Diabetes | 39/2 | 39/4 | 0.52 |
Focal Ischemic Signs (No/Yes) | 29/13 | 25/21 | 0.03 |
Heart Disease (No/Yes) | 35/6 | 38/5 | 0.88 |
BMI | 26.86 ± 4.46 | 27.37 ± 5.22 | 0.61 |
Supine BP Diastolic | 82.38 ± 9.30 | 83.80 ± 12.22 | 0.54 |
Supine BP Systolic | 135.63 ± 13.26 | 135.94 ± 17.93 | 0.93 |
Standing BP Diastolic | 85.41 ± 9.32 | 81.30 ± 12.74 | 0.09 |
Standing BP Systolic | 135.09 ± 13.45 | 124.72 ± 25.05 | 0.01 |
Sitting BP Diastolic | 84.49 ± 9.42 | 82.26 ± 9.76 | 0.27 |
Sitting BP Systolic | 135.51 ± 12.61 | 129.92 ± 14.85 | 0.06 |
BP Fall Diastolic | −3.32 ± 7.79 | 3.82 ± 13.02 | 0.002 |
BP Fall Systolic | −1.29 ± 9.58 | 9.69 ± 16.10 | 0.0001 |
Total Cholesterol | 5.18 ± 1.19 | 4.69 ± 0.87 | 0.02 |
LDL Cholesterol | 3.22 ± 0.96 | 2.85 ± 0.77 | 0.04 |
HDL Cholesterol | 1.33 ± 0.41 | 1.33 ± 0.30 | 0.92 |
Homocysteine | 10.46 ± 2.60 | 13.68 ± 3.76 | <0.0001 |
Triglycerides | 1.37 ± 0.68 | 1.14 ± 0.46 | 0.06 |
Fasting Glucose | 5.55 ± 1.03 | 5.50 ± 0.64 | 0.74 |
APOE: E3/E3, E3/E4, E2/E3, E2/E44 = E4/E4) | 28, 9, 5, 2 | 37, 5, 6, 1 | 0.64 |
UPDRSIII | 1.90 ± 2.79 | 16.89 ± 8.40 | <0.0001 |
Gait Trial Steps | 16.82 ± 3.32 | 21.12 ± 14.00 | 0.05 |
MMSE | 28.45 ± 1.60 | 28.04 ± 1.77 | 0.26 |
Total DRS | 138.56 ± 3.57 | 137.56 ± 4.78 | 0.28 |
Hoehn and Yahr | – | 2.2 ± 0.67 | – |
BMI = Body Mass Index. BP = Blood Pressure. LDL = Low Density Lipoprotein. HDL = High Density Lipoprotein. APOE = Apolipoprotein E. UPDRS = Unified Parkinson's Disease Rating Scale. MMSE = MiniMental State Examination. DRS = Dementia Rating Scale.