Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 May 4;10(3):561–579. doi: 10.1016/j.jcmgh.2020.04.014

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Ebi3 expression does not influence drug-induced metaplasia development. (A) Representative images of H&E-stained sections of the gastric corpus from vehicle-treated BALB/c, HDT-treated BALB/c, and HDT-treated BALB/cxEbi3^-/- mice between 6 and 12 weeks of age showing the degree of parietal cell atrophy induced by tamoxifen relative to vehicle-treated controls. (B) Representative immunofluorescent images of gastric corpus from mice treated as listed earlier. Staining for Hoechst (blue), GIF (yellow), and GSII (green) shows SPEM development. Images are representative of more than 90% of the gastric corpus from 3 mice per experimental group. (C) Quantitation of the average number of GIF+GSII- chief cells (left) and GIF+GSII+ SPEM cells (right) in vehicle-treated BALB/c (Veh) as well as tamoxifen-treated BALB/c and BALB/cxEbi3^-/- mice. Calculated from multiple fields of view in 3 mice per group. Data are means ± SD. Significance was calculated using the Student t test.