Table 2.
Number of Bound Molecules at Early or Late Simulation Times for Small (s1) or Large (s10) Molecules When Scaffolding Sites Were Separated 15 nm (Pbind = 0.9), in Absence or Presence of the Indicated Extra Obstacles at t = 0
| Distance 15 nm | Early Changes (37.5s) | Late Changes (225s) | |
|---|---|---|---|
| s1 | 0 obstacles | 36.80 ± 3.12 | 36.70 ± 3.06 |
| 100 obstacles s1 | 35.30 ± 3.94 (ns) | 36.50 ± 3.74 (ns) | |
| 200 obstacles s1 | 34.40 ± 2.59 (ns) | 38.90 ± 2.80 (ns) | |
| 100 obstacles s10 | 30.90 ± 4.50 (∗∗) | 36.10 ± 2.68 (ns) | |
| 200 obstacles s10 | 29.00 ± 3.02 (∗∗∗∗) | 33.80 ± 3.49 (ns) | |
| s10 | 0 obstacles | 32.70 ± 3.62 | 37.20 ± 3.19 |
| 100 obstacles s1 | 30.30 ± 3.30 (ns) | 34.70 ± 3.62 (ns) | |
| 200 obstacles s1 | 27.50 ± 2.50 (∗∗) | 31.50 ± 3.60 (∗∗) | |
| 100 obstacles s10 | 23.70 ± 4.37 (∗∗∗∗) | 26.10 ± 10.77 (∗∗) | |
| 200 obstacles s10 | 12.60 ± 3.20 (∗∗∗∗) | 20.27 ± 3.13 (∗∗∗∗) | |
Obstacles had the same size of the molecule or not. Mean ± SD, t test against 0 obstacles condition, ns: not significant, ∗∗p < 0.01; ∗∗∗∗p < 0.0001.