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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Tuberculosis (Edinb). 2020 Jun 6;123:101949. doi: 10.1016/j.tube.2020.101949

Figure 4:

Figure 4:

(A) Broncho-alveolar lavage (BAL) fluid from C57BL/6 mice treated with anti-Asialo-GM1 at days 4 and 2 before intranasal inoculation of CpG-C/liposomes/ESAT-6 assayed for IFN-γ, IFN-α, IL-12, TNF-α, MCP-1, and IL-17. Data is from 24 hours post-inoculation. (B) The mycobacterial burden of mice treated with anti-Asialo-GM1 during intranasal inoculation of CpG-C/liposomes/ESAT-6 and infected at day 30 after the last dose with a low dose aerosol of M. tuberculosis H37Rv. Log10 CFU was determined in the lungs and spleens of mice at day 30 post-infection. (C) Cytokine concentration was determined in the lung homogenates from infected mice. Data were analyzed using the One-way ANOVA for independent measures with post-hoc Tukey test. N = 5 mice per group per time point. * = p<0.05, ** = p<0.01