Table 1.
Baseline demographics for our study population.
| All index cases | AD PD index cases | Isolated cases | |
|---|---|---|---|
| n = 1,805 | n = 592 | n = 1,213 | |
| Sex, n (%) | |||
| Male | 1,106 (61.3) | 342 (57.8) | 764 (63) |
| Female | 699 (38.7) | 250 (42.2) | 449 (37) |
| Ancestry, n (%) | |||
| Europeans | 1,530 (84.8) | 525 (88.6) | 1,005 (82.8) |
| North-Africans | 221 (12.2) | 55 (9.3) | 166 (13.7) |
| Other/mixed origins | 42 (2.3) | 11 (1.9) | 31 (2.6) |
| Unknown origins | 12 (0.7) | 1 (0.2) | 11 (0.9) |
| Age at onset, (SD) | 47.4 (12.5) | 50.0 (12.1) | 46.1 (12.5) |
| Range, years | 9–86 | 10–86 | 9–79 |
| Age at examination, (SD) | 55.8 (13.3) | 57.9 (12.5) | 54.9 (13.5) |
| Range, years | 12–88 | 16–88 | 12–85 |
| Early-onset (≤ 50 years), n (%) | 1,065 (62.7) | 311 (54.6) | 754 (66.8) |
| Late-onset (>50 years), n (%) | 634 (37.3) | 259 (45.4) | 375 (33.2) |
| Disease duration, (SD) | 8.4 (6.8) | 7.8 (6.7) | 8.8 (7.4) |
| Range, years | 0–52 | 0–52 | 0–46 |
Frequencies were compared in Fisher's exact tests for qualitative traits and means were compared in Welch's t-tests for continuous variables. Age-at-onset was missing for 106 index cases.
AD, autosomal dominant; PD, Parkinson's disease; SD, standard deviation.