TABLE 2.
Summary of colony formation in soft agar of 16HBE cells treated with Nano-SiO2.
| Treatment Group | Cell number |
Number of Colonies |
||
| 16HBE | 16HBE-ShRNA-NRF2 | 16HBE-pEGFP-NRF2 | ||
| P0 | 1 × 104 | 273 ± 8 | 284 ± 12 | 267 ± 10 |
| P8 | 1 × 104 | 555 ± 32* | 730 ± 30*# | 498 ± 13*# |
| P16 | 1 × 104 | 1141 ± 73* | 1758 ± 108*# | 846 ± 47*# |
| P32 | 1 × 104 | 2161 ± 150* | 2247 ± 64*# | 1486 ± 43*# |
* p < 0.05, compared with normal cells without Nano-SiO2 exposure; # p < 0.05, compared with normal cells treated with Nano-SiO2 for the same passages.