Table 3. Genotype and allele distributions in ApoE genotype groups with ACI patients and controls.
rs2910164 (n) | Genotypes n (%) |
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ApoEε4(−) | CC | GC | GG | p-value | |
ACI (94) | 59 (62.77%) | 28 (29.79%) | 7 (7.45%) | 0.119 | |
Controls (37) | 16 (43.24%) | 16 (43.24%) | 5 (13.51%) | ||
ApoEε4(−) | |||||
ACI (203) | 82 (40.39%) | 100 (49.26%) | 21 (10.34%) | 0.733 | |
Controls (263) | 97 (36.88%) | 136 (51.71%) | 30 (11.41%) | ||
Rs57095329 (n) | Genotypes n (%) |
||||
ApoEε4(−) | AA | GA | GG | p-value | |
ACI (94) | 66 (70.21%) | 27 (28.72%) | 1 (1.06%) | 0.326 | |
Controls (37) | 25 (67.57%) | 10 (27.03%) | 2 (5.41%) | ||
ApoEε4(−) | |||||
ACI (203) | 134 (66.01%) | 60 (29.56%) | 9 (4.43%) | 0.222 | |
Controls (263) | 186 (70.72%) | 72 (27.38%) | 5 (1.90%) | ||
rs2910164 (n) | Alleles n (%) |
||||
ApoEε4(−) | G | C | p-value | OR (95% CI) | |
ACI (94) | 42 (22.24%) | 146 (77.66%) | 0.033* | 0.531 (0.295–0.956) | |
Controls (37) | 26 (35.14%) | 48 (64.87%) | |||
ApoEε4(−) | |||||
ACI (203) | 142 (34.98%) | 264 (65.03%) | 0.472 | 0.906 (0.691–1.186) | |
Controls (263) | 196 (37.26%) | 330 (62.74%) | |||
Rs57095329 (n) | Alleles n (%) |
||||
ApoEε4(−) | G | A | p-value | OR (95% CI) | |
ACI (94) | 29 (15.43%) | 159 (84.57%) | 0.492 | 0.782 (0.387–1.580) | |
Controls (37) | 14 (18.92%) | 60 (81.08%) | |||
ApoEε4(−) | |||||
ACI (203) | 78 (19.21%) | 328 (80.79%) | 0.146 | 1.288 (0.915–1.811) | |
Controls (263) | 82 (15.59%) | 444 (84.41%) | |||
rs2910164 (n) | Recessive model |
||||
ApoEε4(−) | GG−GC .vs. CC | p-value | OR (95% CI) | ||
ACI (94) | 35 (37.24%) | 0.04* | 0.452 (0.209–0.980) | ||
Controls (37) | 21 (56.75%) | ||||
ApoEε4(−) | |||||
ACI (203) | 121 (59.61%) | 0.440 | 0.862 (0.5920–1.256) | ||
Controls (263) | 166 (63.12%) | ||||
Rs57095329 (n) | Recessive model |
||||
ApoEε4(−) | GG−GA. vs. AA | p-value | OR (95% CI) | ||
ACI (94) | 28 (29.897%) | 0.767 | 0.884 (0.390–2.00) | ||
Controls (37) | 12 (32.44%) | ||||
ApoEε4(−) | |||||
ACI (203) | 69 (33.99%) | 0.277 | 1.24 (0.8391–1.844) | ||
Controls (263) | 77 (29.28%) |
Adjusted for age, sex, hypertension and diabetes.
p < 0.05.