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. 2016 Jul 1;23(7):819–829. doi: 10.5551/jat.32904

Table 3. Genotype and allele distributions in ApoE genotype groups with ACI patients and controls.

rs2910164 (n) Genotypes n (%)
ApoEε4(−) CC GC GG p-value

ACI (94) 59 (62.77%) 28 (29.79%) 7 (7.45%) 0.119
Controls (37) 16 (43.24%) 16 (43.24%) 5 (13.51%)
ApoEε4(−)

ACI (203) 82 (40.39%) 100 (49.26%) 21 (10.34%) 0.733
Controls (263) 97 (36.88%) 136 (51.71%) 30 (11.41%)

Rs57095329 (n) Genotypes n (%)
ApoEε4(−) AA GA GG p-value

ACI (94) 66 (70.21%) 27 (28.72%) 1 (1.06%) 0.326
Controls (37) 25 (67.57%) 10 (27.03%) 2 (5.41%)
ApoEε4(−)

ACI (203) 134 (66.01%) 60 (29.56%) 9 (4.43%) 0.222
Controls (263) 186 (70.72%) 72 (27.38%) 5 (1.90%)


rs2910164 (n) Alleles n (%)
ApoEε4(−) G C p-value OR (95% CI)

ACI (94) 42 (22.24%) 146 (77.66%) 0.033* 0.531 (0.295–0.956)
Controls (37) 26 (35.14%) 48 (64.87%)
ApoEε4(−)

ACI (203) 142 (34.98%) 264 (65.03%) 0.472 0.906 (0.691–1.186)
Controls (263) 196 (37.26%) 330 (62.74%)

Rs57095329 (n) Alleles n (%)
ApoEε4(−) G A p-value OR (95% CI)

ACI (94) 29 (15.43%) 159 (84.57%) 0.492 0.782 (0.387–1.580)
Controls (37) 14 (18.92%) 60 (81.08%)
ApoEε4(−)
ACI (203) 78 (19.21%) 328 (80.79%) 0.146 1.288 (0.915–1.811)
Controls (263) 82 (15.59%) 444 (84.41%)


rs2910164 (n) Recessive model
ApoEε4(−) GG−GC .vs. CC p-value OR (95% CI)

ACI (94) 35 (37.24%) 0.04* 0.452 (0.209–0.980)
Controls (37) 21 (56.75%)
ApoEε4(−)

ACI (203) 121 (59.61%) 0.440 0.862 (0.5920–1.256)
Controls (263) 166 (63.12%)

Rs57095329 (n) Recessive model
ApoEε4(−) GG−GA. vs. AA p-value OR (95% CI)

ACI (94) 28 (29.897%) 0.767 0.884 (0.390–2.00)
Controls (37) 12 (32.44%)
ApoEε4(−)

ACI (203) 69 (33.99%) 0.277 1.24 (0.8391–1.844)
Controls (263) 77 (29.28%)

Adjusted for age, sex, hypertension and diabetes.

*

p < 0.05.