Table 2.
Univariate analysis of prognostic factors for OS of the patients.
| Characteristics | N (n of death) | Univariate analysis | ||
|---|---|---|---|---|
| HR | 95% CI | P-value | ||
| Age (years) | 0.531 | 0.208–1.356 | 0.186 | |
| ≥65 | 18 (12) | |||
| <65 | 15 (8) | |||
| Gender | 1.053 | 0.375–2.961 | 0.922 | |
| Male | 26 (15) | |||
| Female | 7 (5) | |||
| Ethnic | 3.492 | 0.799–15.254 | 0.096 | |
| Caucasian | 26 (18) | |||
| Asian | 7 (2) | |||
| Histology | 1.11 | 0.436–2.831 | 0.826 | |
| Pure | 19 1(3) | |||
| Mixed | 14 (7) | |||
| Tumor size (cm) | 0.507 | 0.091–2.828 | 0.439 | |
| ≤ 4 | 7 (2) | |||
| >4 | 8 (3) | |||
| Smoking | 1.205 | 0.229–6.332 | 0.826 | |
| Yes | 6 (4) | |||
| No | 8 (3) | |||
| Pathologic stage | 3.886 | 1.085–13.913 | 0.037* | |
| T1–2 | 10 (3) | |||
| T3–4 | 20 (15) | |||
| Pathologic node status | 3.037 | 0.919–10.041 | 0.069 | |
| N0 | 14 (6) | |||
| N+ | 7 (6) | |||
| Distant metastasis at diagnosis | 8.392 | 2.240–31.434 | 0.002* | |
| M0 | 18 (7) | |||
| M+ | 6 (6) | |||
| Surgery | 1.781 | 0.685–4.634 | 0.237 | |
| RC | 21 (12) | |||
| Bladder-sparing surgery | 11 (7) | |||
| Adjuvant chemotherapy | 2.52 | 1.002–6.333 | 0.049* | |
| Yes | 18 (9) | |||
| No | 15 (11) | |||
| Multimodality therapy | 2.884 | 1.156–7.193 | 0.023* | |
| Yes | 20(10) | |||
| No | 13 (10) | |||
*
P-value, 0.05. RC, radical cystectomy; OS, overall survival. Bold values are statistically significant (p < 0.05).