Table 1.

Multivariate CSF effects on brain morphology along the AD continuum.

	CU	MCI	AD
Age	73.17 (± 6.20)	73.15 (±6.97)	74.83 (±7.84)
Education	16.84 (±2.45)	16.25 (±2.76)	15.85 (±2.65)
Sex (F/M)	170/151	142/190	64/84
# apoE4 (0/1/2)	227/85/9	116/162/54	39/74/35
MMSE	29.04 (±1.22)	27.64 (±1.96)	22.79 (±2.62)
FAQ	0.34 (±1.18)	3.21 (±4.12)	13.97 (±6.84)

Statistical significant ROIs are grouped in 4 clusters characterized by their centroid. We refer to all centroids as the latent pathological patterns driving morphological changes and they are shown in the header of the table.