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. 2020 Jul 28;10:1269. doi: 10.3389/fonc.2020.01269

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Copyright © 2020 Cai, Sun, Wang, Guan, Yue, Li, Wang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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GO enrichment for the pink module and identification of the hub genes. (A) Heatmap for the expression pattern of all genes in pink module at MSI and MSS phenotype. (B,C) The biological process and cellular component for the pink module in GO annotations. (D) The coexpression network for the genes in pink module and identification of the hub genes. (E) The expression of NUBP2, ENDOG, SSNA1 and BCL7C that had been log2 normalized in TCGA-STAD dataset in MSI (N = 51) and MSS group (N = 264). (F) The validation of NUBP2, ENDOG, SSNA1 and BCL7C expression that had been log2 normalized in GSE62254/ACRG in MSI (N = 68) and MSS group (N = 232). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.