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. 2020 Jul 28;11:1131. doi: 10.3389/fphar.2020.01131

Figure 6.

Figure 6

LXA4 antagonizes the effects of GC on trophoblast proliferation and apoptosis in vitro. HTR-8/SVneo cells were treated with Dex (10-7 mol/L) or Dex (10-7 mol/L) plus LXA4 (100 nM) for 24 h in proliferation assay (A) and treated with Dex (10-6 mol/L) or Dex (10-6 mol/L) plus LXA4 (100 nM) for 24 h in apoptosis assay (B). (A) LXA4 reverses the inhibitory effect of Dex on HTR-8/SVneo proliferation; (B) LXA4 inhibits the promotion effect of Dex on HTR-8/SVneo apoptosis. Results are expressed as means ± SEM from three independent experiments. **P < 0.01 versus control group, †P < 0.05 and ††P < 0.01 versus Dex group, one-way ANOVA with S-N-K posttest.