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FRAT2 silencing effects of MDA-MB-231 and T47D cell lines. (A) The three constructed plasmids were introduced into MAD-MB-231 cell lines. The expression level of shFRAT2 was significantly reduced compared with that of the control group (P=0.024). (B) Three of the same plasmids were introduced into T47D cell lines. The expression level of FRAT2 was also reduced (P=0.002). FRAT2, frequently rearranged in advanced T-cell lymphomas 2.
