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. 2020 Jul 7;119(3):493–501. doi: 10.1016/j.bpj.2020.06.027

Figure 8.

Figure 8

(a) Density plot of deformability index versus diameter of MCF-7 cells generated by mDC (reproduced from Fig. 5 d in Masaeli et al. (16) with permission). (b) Numerical scatter plots for MCF-7 cell deformation versus diameter before (squares, circles) and after offset error correction (diamonds). The cell diameter D and shear elasticity G were normally distributed, and the offsets (Yoff and Zoff) were either uniformly distributed (squares) or fixed at a minimal value (Yoff = 0.1 μm and Zoff = 0 μm, circles). The shear elasticity for MCF-7 cells ranged from 200 to 600 Pa, with a mean of 413 Pa and an SD of 100 Pa. The cell diameter range was from 13 to 24 μm, with a mean of 18 μm and an SD of 2 μm. Yoff and Zoff in the fully randomized analysis (squares) varied from 0.1 to 10 μm and 0.1–2.5 μm, respectively. To see this figure in color, go online.