Table 4.
Univariate and multivariate analysis of CD68+ TAMs and clinicopathological factors affecting survival of male patients of GC
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | |
| CD68 (low/high) | 3.843 (1.773–8.329) | 0.001 | 3.905 (1.599–9.538) | 0.003 |
| Age (≤ 60/> 60) | 0.876 (0.441–1.740) | 0.706 | ||
| Diameter(< 5 vs ≥ 5, cm) | 0.308 (0.150–0.636) | 0.001 | 0.393 (0.172–0.901) | 0.027 |
| Lymph node metastasis | ||||
| No/yes | 0.300 (0.133–0.677) | 0.004 | 0.847 (0.328–2.186) | 0.731 |
| Tumour differentiation | ||||
| Low (reference) | 1 | 0.737 | ||
| High | 0.633 (0.186–2.153) | 0.464 | ||
| Moderate | 0.848 (0.402–1.790) | 0.666 | ||
| Invasion depth | ||||
| T4 | 1 | 0.366 | ||
| T1 | 0.000 (0.000–) | 0.975 | ||
| T2 | 0.300 (0.080–1.129) | 0.075 | ||
| T3 | 0.740 (0.332–1.652) | 0.462 | ||
| TNM | ||||
| IV (reference) | 1 | 0.002 | 1 | 0.040 |
| I | 0.000 (0.000–) | 0.978 | 0.000 (0.000–) | 0.977 |
| II | 0.104 (0.030–0.356) | 0.000 | 0.137 (0.035–0.529) | 0.004 |
| III | 0.299 (0.094–0.948) | 0.299 | 0.232 (0.066–0.816) | 0.023 |
Bold italic values indicate significance (p < 0.05)