TABLE 2.
Analyzed parameters | Young | Old | Vehicle | D-gal |
TAC [U/mg protein] | 2.011 ± 0.111 | 1.531 ± 0.118a | 1.888 ± 0.140 | 1.350 ± 0.092a,c |
Total SOD [U/mg protein] | 1.648 ± 0.106 | 1.377 ± 0.115 | 1.619 ± 0.138 | 1.178 ± 0.077a,c |
CAT [U/mg protein] | 7.631 ± 0.630 | 6.29 ± 0.64 | 6.674 ± 0.612 | 4.116 ± 0.307a,b,c |
ROS [AFU/mg protein] | 100 ± 7.84 | 172.37 ± 14.8a | 107.82 ± 11.48 | 204.61 ± 17.01a,c |
H2O2 [nmol/L] | 55.626 ± 7.318 | 75.893 ± 8.521 | 61.907 ± 9.668 | 97.737 ± 7.548a,c |
MDA [nmol/mg protein] | 0.619 ± 0.066 | 1.233 ± 0.073a | 0.746 ± 0.106 | 1.507 ± 0.146a,c |
Hippocampal tissues were from rats aged 3 months (young), 18 months (old), and vehicle- or D-gal-treated rats. n = 8–11 rats/group (for ROS assay, n = 5–6 rats/group). aP < 0.05 when compared with young group. bP < 0.05 when compared with old animals. cP < 0.05 when compared with vehicle-treated control group; one-way ANOVA with Bonferroni’s t-test.