Table 3.
Results of the EORTC QLQ-C30 questionnaire (version 3.0) of patients and the general population.
| Total mean (SD) patients | British participating patients, n = 12 mean (SD) | Dutch participating patients, n = 17 mean (SD) | p value | Dutch general population, n = 170 mean (SD) | British general population, n = 80a mean (SD) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Dyspnoea | 10.3 | (23.7) | 8.0 | (15.1) | 11.8 | (28.7) | 0.845 | 8.2 | (19.1) | 18.7 | (11.8) |
| Insomnia | 31 | (38.8) | 55.6 | (38.4) | 13.7 | (29.0) | 0.004 ∗ | 20.8 | (25.1) | 37.9 | (39.6) |
| Appetite loss | 14.9 | (26.1) | 22.2 | (21.7) | 9.8 | (28.3) | 0.073 | 2.9 | (11.9) | 16.2 | (24.8) |
| Constipationa | 16.7 | (32.1) | 21.2 | (37.3) | 13.7 | (29.0) | 0.781 | 4.7 | (13.7) | 14.6 | (30.9) |
| Diarrhoea | 17.2 | (30.4) | 27.8 | (39.8) | 9.8 | (19.6) | 0.325 | 7.3 | (17.9) | 14.2 | (45.2) |
| Financial difficulties | 11.5 | (24.0) | 22.2 | (29.6) | 3.9 | (16.2) | 0.059 | 5.7 | (18.9) | 23.3 | (34.5) |
| Nausea/vomiting | 7.5 | (17.6) | 13.9 | (24.4) | 2.9 | (8.8) | 0.180 | 4.7 | (13.7) | 14.6 | (28.8) |
| Pain | 33.9 | (36.0) | 58.3 | (37.3) | 16.7 | (23.6) | 0.004 ∗ | 16.2 | (21.9) | 29.4 | (40.3) |
| Fatigue | 31 | (32.9) | 49.1 | (29.0) | 18.3 | (29.9) | 0.004 ∗ | 22.5 | (22.4) | 33.9 | (32.2) |
| Cognitive functioning | 79.9 | (30.3) | 65.3 | (32.1) | 90.2 | (25.0) | 0.030 ∗ | 91.7 | (15.7) | 76.7 | (29.5) |
| Emotional functioning | 73.6 | (32.4) | 59.0 | (33.6) | 83.8 | (28.2) | 0.021 ∗ | 84.3 | (18.9) | 67.3 | (36.7) |
| Social functioning | 77.6 | (29.6) | 58.3 | (33) | 91.2 | (17.8) | 0.001 ∗ | 94.2 | (14.9) | 75.4 | (38.8) |
| Physical functioning | 75.2 | (27.9) | 67.8 | (32.5) | 80.3 | (23.9) | 0.394 | 92.5 | (13.1) | 80.2 | (33.3) |
| Role functioning | 71.8 | (32.8) | 52.8 | (40.1) | 85.3 | (17.6) | 0.027 ∗ | 91.8 | (19.5) | 76.5 | (38.8) |
| Global health status | 68.7 | (27.7) | 56.9 | (29.5) | 77.0 | (23.9) | 0.043 ∗ | 78.7 | (18.2) | 60.2 | (34.6) |
| Summary score | 78.1 | 63.5 | 87.2 | 89.8 | 76.7 | ||||||
aData missing from 1 British patient; ∗statistically significant difference. Mean scores with standard deviation (SD) are displayed for all scales of the EORTC QLQ-C30. The p value represents the comparison of the scores of the British participating patients versus the scores of the Dutch participating patients. Two-sided p < 0.05 was considered statistically significant.