Table II.

Association between ANGPTL4 expression and clinical parameters in 205 patients with invasive ductal carcinoma.

	ANGPTL4 expression, n
Variable	Negative	Weakly positive	Moderately positive	Strongly positive	P-value
Age, years					0.371
<55	38	28	30	12
≥55	37	25	22	13
Tumor size, cm					<0.001
≤2.0	46	10	15	7
2.1–5.0	29	41	30	8
>5.0	0	2	7	10
pTNM					<0.001
I	30	6	4	0
II	29	38	28	7
III	16	7	14	12
IV	0	2	6	6
Grade					<0.001
I	25	8	4	0
II	34	31	31	15
III	16	14	17	10
ER					0.955
–	38	29	28	12
+	37	24	24	13
PR					0.793
–	41	30	22	18
+	34	23	30	7
HER2					0.211
–	35	32	22	9
1+	16	5	18	8
2+	14	4	6	4
3+	10	12	6	4
Lymph node metastasis					<0.001
–	51	29	25	6
+	24	24	27	19
Distant metastasis					<0.001
–	68	46	37	15
+	7	7	15	10
Local recurrence
–	75	51	48	19	<0.001
+	0	2	4	6

ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2; ANGPTL4, angiopoietin-like 4.