Table II.
Mammography, MRI and pathological characteristics of 9 cases of IMPC.
| Pathology | |||||||
|---|---|---|---|---|---|---|---|
| Patient no. | Diameter, mm | Mammography | ADC of MRI, ×10−3 mm2/sec | LVI | LNM | IC components | Immunohistochemistry |
| 1 | 13.2 | High density, irregular shape, burr edge | 0.681 | – | – | – | ER+, PR−, Her-2−, Ki-67 (30%) |
| 2 | 19.2 | N/A | 0.882 | – | + | – | ER+, PR+, Her-21+, Ki-67 (30%) |
| 3 | 64.2 (largest of 3 lesions) | High density, lobulated, unclear edge, thickened adjacent skin, depression | 0.613 | + | + | – | ER+, PR+, Her-22+, Ki-67 (10%), no HER2 amplification FISH |
| 4 | 15 | High density, irregular shape, blurry edges | 0.849 | – | + | + | ER+, PR+, Her-2−, Ki-67 (15%) |
| 5 | 85.4 | Large pieces of asymmetrical and dense lesions, with regional distribution of fine pleomorphic calcification, thickened local skin, nipple retraction | 0.989 | + | + | – | ER+, PR+, Her-22+, Ki-67 (70-80%), HER2 amplification on FISH |
| 6 | 44.9 | High density, irregular shape, burr edge, visible fine calcification of the segmental distribution | 0.838 | – | + | + | ER+, PR+, Her-2−, Ki-67 (10%) |
| 7 | 16.2 | N/A | 0.778 | – | – | + | ER+, PR+, Her-2−, Ki-67 (10%) |
| 8 | 17.4 | Under the left armpit, increased density, unclear edges, several lymph nodes displayed around | 0.955 | + | + | – | ER+, PR+, Her-22+, Ki-67 (20%), no HER2 amplification on FISH |
| 9 | 27.7 | High density, irregular shape, unclear edge, small pleomorphic calcification around the segment, thickening near the local areola skin | N/A | – | + | – | ER+, PR+, Her-23+, Ki-67 (20%) |
MRI, magnetic resonance imaging; IMPC, invasive micropapillary carcinoma; ADC, apparent diffusion coefficient; LVI, lymphovascular invasion; LNM, lymph node metastasis; IC, intraductal cancer; ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2; FISH, fluorescence in situ hybridization; N/A, not applicable.