Table 1.

Identified Anisakis spp. EV proteins cross-referenced to published helminth EV proteomes.

Accession	Protein	Reference 1
A0A0M3K8U5	14-3-3	[30,31,32,33]
A0A0M3K9V2	HSP70	[5,6,30,32,33]
A0A0M3IZK3	Tubulin beta	[6,30,31,34]
A0A0M3K9P2	CBN-exc 4	[6,30,31,32] 2
A0A0M3KB40; A0A0M3J0M4	Actin	[5,6,33,34]
A0A0M3KFX3	Ras like protein 3	[31]
A0A0M3J8F3; A0A0M3JD57; A0A0M3K4N2; A0A0M3KAB8; A0A0M3KCN6; A0A158PMY7	Maltase glucoamylase	[6]
A0A0M3J727; A0A0M3KA60	Histidine acid phosphatase	[5,6,30,32] 3
A0A0M3JAF9	Prostatic acid phosphatase	[5,30,32] 3
A0A0M3K4H2	Glutamate dehydrogenase	[6,30,32]
A0A0M3JY91; A0A0M3K219	ATP synthase F1 (alpha + beta subunit)	[6]
A0A0M3JYW4	RAS-like GTP-binding protein RhoA	[6,30]
A0A0M3J718; A0A0M3JZV6	Superoxide dismutase	[32]
A0A0M3JVA0	ADP ribosylation factor 1	[34]
A0A0M3JAH0	Pepsin inhibitor	[32]

¹ References for homologous proteins identified in EV proteomes of H. polygyrus [5], F. hepatica [30,31], T. muris [32], A. suum [6], S. mansoni [33] and T. circumcincta [34]. ² Chloride channel exc identified in [31], C-exl 1 identified in [6]. Alternative chloride channels identified e.g CLCN7 [29,30]. ³ Identified in references as lysosomal acid phosphatase or acid phosphatase.