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. 2020 Jun 29;12(7):1927. doi: 10.3390/nu12071927

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Inhibitory effects of WELC on OVX-induced fat accumulation. Sham or OVX mice were administered vehicle, WELC-L (100 mg/kg), or WELC-H (300 mg/kg) for five weeks. (A) Body weight gain during the experimental period, (B) uterine weight, and (C) gonadal fat weight were measured. (D) Histological analysis of adipose tissue, liver, and bone was performed using hematoxylin and eosin staining (scale bar, 100 µm). Image analysis of the adipocyte area or lipid droplets in each tissue was performed using the ImageJ program. * p < 0.05, ** p < 0.01 versus OVX group. WELC, water extract of Lysimachia christinae; OVX, ovariectomized.

Inhibitory effects of WELC on OVX-induced fat accumulation. Sham or OVX mice were administered vehicle, WELC-L (100 mg/kg), or WELC-H (300 mg/kg) for five weeks. (A) Body weight gain during the experimental period, (B) uterine weight, and (C) gonadal fat weight were measured. (D) Histological analysis of adipose tissue, liver, and bone was performed using hematoxylin and eosin staining (scale bar, 100 µm). Image analysis of the adipocyte area or lipid droplets in each tissue was performed using the ImageJ program. * p < 0.05, ** p < 0.01 versus OVX group. WELC, water extract of Lysimachia christinae; OVX, ovariectomized.