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. 2020 Jul 17;8(7):224. doi: 10.3390/biomedicines8070224

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(A) Subunit architecture of F_OF₁ ATP synthase from E. coli. The bottom panel depicts membrane vesicle-bound F_OF₁ under different experimental conditions. (B) HDX levels of I_ADP for an HDX period of 45 min. (C) Deuteration difference map of W_PMF vs. I_ADP. (D) Deuteration difference map of W_FCCP vs. I_ADP. Regions that were not covered are shown in dark gray. Colors represent deuteration percentages or HDX difference (%) as indicated in the legends. Reproduced with permission from the National Academy of Sciences (© 2016).